For opioids with long half-lives i. Various routes of administration and the management of drug side effects are discussed. Furthermore, because many intractable pain problems involve neurologic structures e.
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Management involves the aggressive use of analgesics such as systemic patient-controlled analgesia and agent-specific antimicrobial agents Epstein, ; Janjan, Weissman, and Pahule,
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Initially, the mucosa in the path of radiation appears reddened and swollen; as treatment continues, the mucosa can be covered with a fibrous exudate. When developing a treatment plan, clinicians should be aware of the unique needs and circumstances of patients from different age groups or various ethnic and cultural backgrounds.
The coadministration of systemic opioids which generally is not recommended for postoperative pain management is safe in most cancer patients because they are tolerant to the respiratory-depressant effects of the drugs. The panel recommends that laws and regulatory policies aimed at diversion control not hamper the appropriate use of opioid analgesics for cancer pain.
General Anesthesia, Sleep, and Coma
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